Job Description

Global Therapeutic Research Lead Immunology

Cambridge, MA Fulltime Employee Base pay range: $208,200.00 $327,140.00 /yr

On the 2day basis, early applicants are prioritized. Your exact pay will be determined by skills, experience, and the roles requirements.

Job Description

At Takeda, our forwardlooking R&D organization unlocks innovation and delivers transformative therapies worldwide, focusing on gastroenterology, inflammation and immunology. This role leads discovery programs that progress to clinic.

Purpose

• Leverage a proven track record to lead at least three discovery programs to clinic within the Gastroenterology and Inflammation Drug Discovery Unit (GI DDU).
• Steer at least one or more toppriority projects with clear, accelerated paths to clinic and substantial clinical and commercial potential.
• Mentor and elevate enterprise thinking among global discovery talent.
• Build a connected view of projects with strategy, treatment paradigms, and stakeholder alignment across Research, Clinical Development, and Commercial functions.
• Create vision and early asset strategy, managing external partnerships to accelerate delivery.
• Establish smart, fast, and criticalpath practices, integrating new strategies and industry best practices.
• Advise on continuous infusion of new research projects aligned to strategy to sustain a highquality IND pipeline.

Accountabilities

• Lead and manage one or more Top 10 programsfrom target identification through preclinical developmentensuring strategic alignment and clinical potential.
• Own and articulate project strategy in partnership with internal stakeholders.
• Contribute to broader portfolio investment strategy, especially within Inflammation and Immunology.
• Evaluate and prioritize drug candidates based on scientific, medical, and commercial considerations.
• Represent core expertise to crossfunctional teams.
• Partner with Clinical and Translational teams to refine asset strategy and ensure alignment with therapeutic area strategy.
• Align with commercial team on asset value within the therapeutic area.
• Mentor global project members, fostering enterprise thinking and professional growth.
• Collaborate with DMPK, Pharmaceutical Sciences, and external partners to drive delivery.
• Provide strategic, process, and operational leadership for Top10 project delivery.
• Encourage a culture of innovation, scientific excellence, and continuous learning within the matrixed team.
• Serve as a leading scientific expert for projects and guide decisionmaking through data analysis and interpretation.
• Stay abreast of advancements in drug discovery, emerging technologies, and industry trends.
• Build and maintain relationships with academic institutions, research organizations, and industry partners, serving on external governance committees.
• Act as an external ambassador for Takedas GI DDU and lead global business development evaluations.

Education & Competencies (Technical and Behavioral)

• PhD with 15+ years of experience;MS with 21+ years;BS with 23+ years (expected).
• 1012+ years of industry experience in Immunology/Inflammation and global management in matrix teams.
• Extensive experience leading drug discovery teams, preferably in gastroenterology and inflammation.
• Deep understanding of discovery process: target identification, hittolead, preclinical development.
• Proven track record of leading 5 discovery projects from inception to candidate nomination.
• Major role in 3 INDs.
• Clinical development experience, especially biologics and multiple modalities.
• Inclusive leadership that inspires diverse teams toward ambitious goals.
• Proactive, solutionsoriented engagement across organizational expertise.
• Business acumen, regulatory understanding, and commercial insight for specific modalities.
• Exceptional communication and presentation skills for complex scientific concepts.
• Ability to build and maintain collaborative relationships with internal and external stakeholders.
• Strong problemsolving and datadriven decision making.
• Experience building and managing strategic partnerships with academia and industry.

Additional Information

• Position based in Cambridge, MA classified as hybrid per Takedas workpolicy.

Takeda Compensation and Benefits Summary

We value equitable pay and transparency. Salary is based on qualifications, experience, and location. U.S. employees may qualify for shortterm and longterm incentives, as well as medical, dental, vision, 401(k) with company match, disability, life, tuition reimbursement, paid volunteer time, holidays, wellbeing programs, sick time, and vacation.

EEO Statement

Takeda is proud of its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information, marital status, veteran status, or any other characteristic protected by law.

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